What Diseases Can Raccoons Transmit to Humans? Raccoons carry numerous diseases that can be detrimental to both human and pet health, and transmission is usually the result of incorrect handling of the pests, which leads to bites or scratches, or direct contact with their feces: Rabies - spread via saliva and causes muscle pain, dizziness, fatigue, loss of appetite, fever, delirium, and irritability. Raccoon Roundworm - also known as baylisascaris, this parasite is found in the pest's feces and induces unpleasant symptoms like liver enlargement, loss of muscle control, blindness, and disorientation. Leptospirosis - bacteria spread via excrement which causes fever, headache, chills, muscle aches, jaundice, and potentially even kidney or liver failure. Giardiasis - gastrointestinal ailment that induces bloating, vomiting, indigestion, and loss of appetite in those afflicted. Salmonellosis - when ingested, the Salmonella bacteria brings about abdominal pain and diarrhea.