What Does an Opossum Sound Like? Opossum Audio Thought you heard a opossum? Listen to an audio recording (mp3 file) of opossum noises and sounds. Opossum Opossums make nests in dens left by other animals, crevices in trees, attics, and garages. The pests live near suburbs and cities where they can raid garbage bins and feed on roadkill. They do most of their scavenging at night because they're nocturnal. Notably, opossums are skittish and are prey for several other wildlife pests. Opossum Noises These pests will make clicking noises when they're trying to attract mates and hissing or growling sounds when they feel threated. Baby opossums make noises that sound like sneezing when trying to get their parents' attention. Outside of these special circumstances, though, the pests rarely make audible sounds. Control & Removal Infestations of opossums trash yards, scatter trash outside and inside homes, and dirty basements and attics when they use these spaces for nesting and birthing. If landowners notice opossum activity, they should seek professional removal assistance from Critter Control specialists. Never handle wild opossums. Instead, rely on experts to take care of any problems.